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HNRNPU promotes the progression of triple-negative breast cancer via RNA transcription and alternative splicing mechanisms

Triple-negative breast cancer (TNBC) is a great detriment to women’s health due to the lack of effective therapeutic targets. In this study, we employed an integrated genetic screen to identify a pivotal oncogenic factor, heterogeneous nuclear ribonucleoprotein U (HNRNPU), which is required for the...

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Detalles Bibliográficos
Autores principales: Han, Bo-yue, Liu, Zhebin, Hu, Xin, Ling, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643420/
https://www.ncbi.nlm.nih.gov/pubmed/36347834
http://dx.doi.org/10.1038/s41419-022-05376-6