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HNRNPU promotes the progression of triple-negative breast cancer via RNA transcription and alternative splicing mechanisms
Triple-negative breast cancer (TNBC) is a great detriment to women’s health due to the lack of effective therapeutic targets. In this study, we employed an integrated genetic screen to identify a pivotal oncogenic factor, heterogeneous nuclear ribonucleoprotein U (HNRNPU), which is required for the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643420/ https://www.ncbi.nlm.nih.gov/pubmed/36347834 http://dx.doi.org/10.1038/s41419-022-05376-6 |