CDKN1A is a target for phagocytosis-mediated cellular immunotherapy in acute leukemia

Targeting the reprogramming and phagocytic capacities of tumor-associated macrophages (TAMs) has emerged as a therapeutic opportunity for cancer treatment. Here, we demonstrate that tumor cell phagocytosis drives the pro-inflammatory activation of TAMs and identify a key role for the cyclin-dependen...

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Detalles Bibliográficos
Autores principales: Allouch, Awatef, Voisin, Laurent, Zhang, Yanyan, Raza, Syed Qasim, Lecluse, Yann, Calvo, Julien, Selimoglu-Buet, Dorothée, de Botton, Stéphane, Louache, Fawzia, Pflumio, Françoise, Solary, Eric, Perfettini, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643439/
https://www.ncbi.nlm.nih.gov/pubmed/36347876
http://dx.doi.org/10.1038/s41467-022-34548-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643439/
https://www.ncbi.nlm.nih.gov/pubmed/36347876
http://dx.doi.org/10.1038/s41467-022-34548-3

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