The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism

Inhibition of the mitochondrial metabolism offers a promising therapeutic approach for the treatment of cancer. Here, we identify the mycotoxin viriditoxin (VDT), derived from the endophytic fungus Cladosporium cladosporioides, as an interesting candidate for leukemia and lymphoma treatment. VDT dis...

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Detalles Bibliográficos
Autores principales: Stuhldreier, Fabian, Schmitt, Laura, Lenz, Thomas, Hinxlage, Ilka, Zimmermann, Marcel, Wollnitzke, Philipp, Schliehe-Diecks, Julian, Liu, Yang, Jäger, Paul, Geyh, Stefanie, Teusch, Nicole, Peter, Christoph, Bhatia, Sanil, Haas, Rainer, Levkau, Bodo, Reichert, Andreas S., Stühler, Kai, Proksch, Peter, Stork, Björn, Wesselborg, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643474/
https://www.ncbi.nlm.nih.gov/pubmed/36347842
http://dx.doi.org/10.1038/s41419-022-05356-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643474/
https://www.ncbi.nlm.nih.gov/pubmed/36347842
http://dx.doi.org/10.1038/s41419-022-05356-w

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