Deep learning-based image analysis predicts PD-L1 status from H&E-stained histopathology images in breast cancer

Programmed death ligand-1 (PD-L1) has been recently adopted for breast cancer as a predictive biomarker for immunotherapies. The cost, time, and variability of PD-L1 quantification by immunohistochemistry (IHC) are a challenge. In contrast, hematoxylin and eosin (H&E) is a robust staining used r...

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Detalles Bibliográficos
Autores principales: Shamai, Gil, Livne, Amir, Polónia, António, Sabo, Edmond, Cretu, Alexandra, Bar-Sela, Gil, Kimmel, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643479/
https://www.ncbi.nlm.nih.gov/pubmed/36347854
http://dx.doi.org/10.1038/s41467-022-34275-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643479/
https://www.ncbi.nlm.nih.gov/pubmed/36347854
http://dx.doi.org/10.1038/s41467-022-34275-9

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