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EFEMP1 binds to STEAP1 to promote osteosarcoma proliferation and invasion via the Wnt/β-catenin and TGF-β/Smad2/3 signal pathways

PURPOSE: To investigate the prognostic value and function of six-transmembrane epithelial antigen of prostate 1 (STEAP1) in osteosarcoma and determine whether EFEMP1 mediates its effects. METHODS: IHC (immunohistochemistry)/ICC (immunocytochemistry) in conjunction with RT-qPCR (quantitative real-tim...

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Detalles Bibliográficos
Autores principales: Zhang, Dong, Han, Shasha, Pan, Xin, Li, Hao, Zhao, Hua, Gao, Xianlei, Wang, Songgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643485/
https://www.ncbi.nlm.nih.gov/pubmed/36388640
http://dx.doi.org/10.1016/j.jbo.2022.100458