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Single cell sequencing reveals that CD39 inhibition mediates changes to the tumor microenvironment

Single-cell sequencing technologies have noteworthily improved our understanding of the genetic map and molecular characteristics of bladder cancer (BC). Here we identify CD39 as a potential therapeutic target for BC via single-cell transcriptome analysis. In a subcutaneous tumor model and orthotopi...

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Detalles Bibliográficos
Autores principales: Liu, Lilong, Hou, Yaxin, Deng, Changqi, Tao, Zhen, Chen, Zhaohui, Hu, Junyi, Chen, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643495/
https://www.ncbi.nlm.nih.gov/pubmed/36347860
http://dx.doi.org/10.1038/s41467-022-34495-z