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Effect of histone deacetylase inhibitor (vorinostat) on new-onset diabetes induced by tacrolimus

OBJECTIVE: The immunosuppressant tacrolimus is a major cause of new-onset diabetes after transplantation. The aim of this study was to evaluate whether a low dose of the histone-deacetylase inhibitor (vorinostat) might ameliorate tacrolimus-induced new-onset diabetes. METHODS: Thirty 8-week-old male...

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Detalles Bibliográficos
Autores principales: Bakhdar, Fatmah A., Abdel kawy, Hala S., Magadmi, Rania M., El-Kordy, Eman A., Alamri, Abdulhakeem S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taibah University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643516/
https://www.ncbi.nlm.nih.gov/pubmed/36398015
http://dx.doi.org/10.1016/j.jtumed.2022.07.004