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Beyond fundamental resonance mode: high-order multi-band ALN PMUT for in vivo photoacoustic imaging

This paper reports on an aluminum nitride (AlN) piezoelectric micromachined ultrasound transducer (PMUT) array for photoacoustic (PA) imaging, where the high-order resonance modes of the PMUT are utilized to improve imaging resolution. A flexural vibration mode (FVM) PMUT is fabricated and applied i...

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Autores principales: Cai, Junxiang, Wang, Yiyun, Jiang, Daohuai, Zhang, Songsong, Gu, Yuandong Alex, Lou, Liang, Gao, Fei, Wu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643525/
https://www.ncbi.nlm.nih.gov/pubmed/36389053
http://dx.doi.org/10.1038/s41378-022-00426-7
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author Cai, Junxiang
Wang, Yiyun
Jiang, Daohuai
Zhang, Songsong
Gu, Yuandong Alex
Lou, Liang
Gao, Fei
Wu, Tao
author_facet Cai, Junxiang
Wang, Yiyun
Jiang, Daohuai
Zhang, Songsong
Gu, Yuandong Alex
Lou, Liang
Gao, Fei
Wu, Tao
author_sort Cai, Junxiang
collection PubMed
description This paper reports on an aluminum nitride (AlN) piezoelectric micromachined ultrasound transducer (PMUT) array for photoacoustic (PA) imaging, where the high-order resonance modes of the PMUT are utilized to improve imaging resolution. A flexural vibration mode (FVM) PMUT is fabricated and applied in a photoacoustic imaging (PAI) system. Specifically, the microelectromechanical system (MEMS)-based PMUT is suitable for PA endoscopic imaging of blood vessels and bronchi due to its miniature size and high sensitivity. More importantly, AlN is a nontoxic material, which makes it harmless for biomedical applications. In the PAI system, the AlN PMUT array is used to detect PA signals, and the acousto–mechanical response is designed and optimized at the PMUT’s fundamental resonance. In this work, we focus on the high-order resonance performance of the PMUT PAI beyond the fundamental resonance. The acoustic and electrical responses of the PMUT’s high-order resonance modes are characterized and analyzed. The fundamental and three high-order resonance bandwidths are 2.2, 8.8, 18.5, and 48.2 kHz. Compared with the resolution at the fundamental resonance mode, the resolutions at third- and fourth-order resonance modes increase by 38.7% and 76.9% in a phantom experiment. The high-order resonance modes of the AlN PMUT sensor array provide higher central frequency and wider bandwidth for PA signal detection, which increase the resolution of PAI compared to the PMUT working at the fundamental resonance mode. [Image: see text]
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spelling pubmed-96435252022-11-15 Beyond fundamental resonance mode: high-order multi-band ALN PMUT for in vivo photoacoustic imaging Cai, Junxiang Wang, Yiyun Jiang, Daohuai Zhang, Songsong Gu, Yuandong Alex Lou, Liang Gao, Fei Wu, Tao Microsyst Nanoeng Article This paper reports on an aluminum nitride (AlN) piezoelectric micromachined ultrasound transducer (PMUT) array for photoacoustic (PA) imaging, where the high-order resonance modes of the PMUT are utilized to improve imaging resolution. A flexural vibration mode (FVM) PMUT is fabricated and applied in a photoacoustic imaging (PAI) system. Specifically, the microelectromechanical system (MEMS)-based PMUT is suitable for PA endoscopic imaging of blood vessels and bronchi due to its miniature size and high sensitivity. More importantly, AlN is a nontoxic material, which makes it harmless for biomedical applications. In the PAI system, the AlN PMUT array is used to detect PA signals, and the acousto–mechanical response is designed and optimized at the PMUT’s fundamental resonance. In this work, we focus on the high-order resonance performance of the PMUT PAI beyond the fundamental resonance. The acoustic and electrical responses of the PMUT’s high-order resonance modes are characterized and analyzed. The fundamental and three high-order resonance bandwidths are 2.2, 8.8, 18.5, and 48.2 kHz. Compared with the resolution at the fundamental resonance mode, the resolutions at third- and fourth-order resonance modes increase by 38.7% and 76.9% in a phantom experiment. The high-order resonance modes of the AlN PMUT sensor array provide higher central frequency and wider bandwidth for PA signal detection, which increase the resolution of PAI compared to the PMUT working at the fundamental resonance mode. [Image: see text] Nature Publishing Group UK 2022-11-09 /pmc/articles/PMC9643525/ /pubmed/36389053 http://dx.doi.org/10.1038/s41378-022-00426-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Cai, Junxiang
Wang, Yiyun
Jiang, Daohuai
Zhang, Songsong
Gu, Yuandong Alex
Lou, Liang
Gao, Fei
Wu, Tao
Beyond fundamental resonance mode: high-order multi-band ALN PMUT for in vivo photoacoustic imaging
title Beyond fundamental resonance mode: high-order multi-band ALN PMUT for in vivo photoacoustic imaging
title_full Beyond fundamental resonance mode: high-order multi-band ALN PMUT for in vivo photoacoustic imaging
title_fullStr Beyond fundamental resonance mode: high-order multi-band ALN PMUT for in vivo photoacoustic imaging
title_full_unstemmed Beyond fundamental resonance mode: high-order multi-band ALN PMUT for in vivo photoacoustic imaging
title_short Beyond fundamental resonance mode: high-order multi-band ALN PMUT for in vivo photoacoustic imaging
title_sort beyond fundamental resonance mode: high-order multi-band aln pmut for in vivo photoacoustic imaging
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643525/
https://www.ncbi.nlm.nih.gov/pubmed/36389053
http://dx.doi.org/10.1038/s41378-022-00426-7
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