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FMR1 promotes the progression of colorectal cancer cell by stabilizing EGFR mRNA in an m(6)A-dependent manner

FMR1, a new m(6)A reader, is known to be involved in the regulation of cancer progression. However, its role, regulatory mechanism, and clinical significance in colorectal cancer (CRC) are elusive. Here, we showed that FMR1 was upregulated in CRC, and it promoted proliferation and metastasis of CRC...

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Detalles Bibliográficos
Autores principales: Hu, Yuhan, Gao, Qingzu, Ma, Shuai, Yu, Pei, Ding, Shuang, Yao, Xiaofei, Zhang, Zheying, Lu, Shuya, Lu, Manman, Zhang, Jinghang, Wang, Yanling, Qian, Xinlai, Zhong, Jiateng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643526/
https://www.ncbi.nlm.nih.gov/pubmed/36347844
http://dx.doi.org/10.1038/s41419-022-05391-7