CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever

Dengue virus infection can cause dengue hemorrhagic fever (DHF). Dengue NS1 is multifunctional. The intracellular dimeric NS1 (iNS1) forms part of the viral replication complex. Previous studies suggest the extracellular secreted NS1 (sNS1), which is a major factor contributing to DHF, exists as hex...

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Detalles Bibliográficos
Autores principales: Shu, Bo, Ooi, Justin S. G., Tan, Aaron W. K., Ng, Thiam-Seng, Dejnirattisai, Wanwisa, Mongkolsapaya, Juthathip, Fibriansah, Guntur, Shi, Jian, Kostyuchenko, Victor A., Screaton, Gavin R., Lok, Shee-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643530/
https://www.ncbi.nlm.nih.gov/pubmed/36347841
http://dx.doi.org/10.1038/s41467-022-34415-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643530/
https://www.ncbi.nlm.nih.gov/pubmed/36347841
http://dx.doi.org/10.1038/s41467-022-34415-1

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