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CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever
Dengue virus infection can cause dengue hemorrhagic fever (DHF). Dengue NS1 is multifunctional. The intracellular dimeric NS1 (iNS1) forms part of the viral replication complex. Previous studies suggest the extracellular secreted NS1 (sNS1), which is a major factor contributing to DHF, exists as hex...
Autores principales: | Shu, Bo, Ooi, Justin S. G., Tan, Aaron W. K., Ng, Thiam-Seng, Dejnirattisai, Wanwisa, Mongkolsapaya, Juthathip, Fibriansah, Guntur, Shi, Jian, Kostyuchenko, Victor A., Screaton, Gavin R., Lok, Shee-Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643530/ https://www.ncbi.nlm.nih.gov/pubmed/36347841 http://dx.doi.org/10.1038/s41467-022-34415-1 |
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