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Age- and sex-specific effects of maternal separation on the acoustic startle reflex in rats: early baseline enhancement in females and blunted response to ambiguous threat

Early life adversity (ELA) increases the incidence of later-life anxiety disorders. Dysregulated threat processing, including responsivity to ambiguous threats, is an indicator of anxiety disorders and can be influenced by childhood experiences. The acoustic startle response is a defensive reflex di...

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Detalles Bibliográficos
Autores principales: Granata, Lauren, Parakoyi, Abigail, Brenhouse, Heather C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643533/
https://www.ncbi.nlm.nih.gov/pubmed/36386786
http://dx.doi.org/10.3389/fnbeh.2022.1023513