Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding

OBJECTIVE: Identifying the transcripts which mediate genetic association signals for type 2 diabetes (T2D) is critical to understand disease mechanisms. Studies in pancreatic islets support the transcription factor ZMIZ1 as a transcript underlying a T2D GWAS signal, but how it influences T2D risk is...

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Detalles Bibliográficos
Autores principales: Alghamdi, Tamadher A., Krentz, Nicole A.J., Smith, Nancy, Spigelman, Aliya F., Rajesh, Varsha, Jha, Alokkumar, Ferdaoussi, Mourad, Suzuki, Kunimasa, Yang, Jing, Manning Fox, Jocelyn E., Sun, Han, Sun, Zijie, Gloyn, Anna L., MacDonald, Patrick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643564/
https://www.ncbi.nlm.nih.gov/pubmed/36307047
http://dx.doi.org/10.1016/j.molmet.2022.101621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643564/
https://www.ncbi.nlm.nih.gov/pubmed/36307047
http://dx.doi.org/10.1016/j.molmet.2022.101621

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