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Proteophenes – Amino Acid Functionalized Thiophene‐based Fluorescent Ligands for Visualization of Protein Deposits in Tissue Sections with Alzheimer's Disease Pathology

Protein deposits composed of specific proteins or peptides are associated with several neurodegenerative diseases and fluorescent ligands able to detect these pathological hallmarks are vital. Here, we report the synthesis of a class of thiophene‐based ligands, denoted proteophenes, with different a...

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Detalles Bibliográficos
Autores principales: Björk, Linnea, Bäck, Marcus, Lantz, Linda, Ghetti, Bernardino, Vidal, Ruben, Klingstedt, Therése, Nilsson, K. Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643645/
https://www.ncbi.nlm.nih.gov/pubmed/35950816
http://dx.doi.org/10.1002/chem.202201557