Engineering Enzyme Substrate Scope Complementarity for Promiscuous Cascade Synthesis of 1,2‐Amino Alcohols

Biocatalytic cascades are uniquely powerful for the efficient, asymmetric synthesis of bioactive compounds. However, high substrate specificity can hinder the scope of biocatalytic cascades because the constituent enzymes may have non‐complementary activity. In this study, we implemented a substrate...

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Detalles Bibliográficos
Autores principales: McDonald, Allwin D., Bruffy, Samantha K., Kasat, Aadhishre T., Buller, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643649/
https://www.ncbi.nlm.nih.gov/pubmed/36136093
http://dx.doi.org/10.1002/anie.202212637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643649/
https://www.ncbi.nlm.nih.gov/pubmed/36136093
http://dx.doi.org/10.1002/anie.202212637

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