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Disturbed natural killer cell homeostasis in the salivary gland enhances autoimmune pathology via IFN-γ in a mouse model of primary Sjögren’s syndrome

OBJECTIVE: Innate lymphoid cells (ILCs), including natural killer (NK) cells, ILC1, ILC2, lymphoid tissue-inducer (LTi) cells, and ILC3 cell, play a key role in various immune responses. Primary Sjögren’s syndrome (pSS) is an autoimmune disease characterized by chronic inflammation of exocrine gland...

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Detalles Bibliográficos
Autores principales: Sato, Mami, Arakaki, Rieko, Tawara, Hiroaki, Nagao, Ruka, Tanaka, Hidetaka, Tamura, Kai, Kawahito, Yuhki, Otsuka, Kunihiro, Ushio, Aya, Tsunematsu, Takaaki, Ishimaru, Naozumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643684/
https://www.ncbi.nlm.nih.gov/pubmed/36388880
http://dx.doi.org/10.3389/fmed.2022.1036787