Cargando…

Disturbed natural killer cell homeostasis in the salivary gland enhances autoimmune pathology via IFN-γ in a mouse model of primary Sjögren’s syndrome

OBJECTIVE: Innate lymphoid cells (ILCs), including natural killer (NK) cells, ILC1, ILC2, lymphoid tissue-inducer (LTi) cells, and ILC3 cell, play a key role in various immune responses. Primary Sjögren’s syndrome (pSS) is an autoimmune disease characterized by chronic inflammation of exocrine gland...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sato, Mami, Arakaki, Rieko, Tawara, Hiroaki, Nagao, Ruka, Tanaka, Hidetaka, Tamura, Kai, Kawahito, Yuhki, Otsuka, Kunihiro, Ushio, Aya, Tsunematsu, Takaaki, Ishimaru, Naozumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643684/ https://www.ncbi.nlm.nih.gov/pubmed/36388880 http://dx.doi.org/10.3389/fmed.2022.1036787

Ejemplares similares

CD4(+) T-cell-dependent differentiation of CD23(+) follicular B cells contributes to the pulmonary pathology in a primary Sjögren’s syndrome mouse model
por: Sato-Fukuba, Mami, et al.
Publicado: (2023)

CCL22-Producing Resident Macrophages Enhance T Cell Response in Sjögren's Syndrome
por: Ushio, Aya, et al.
Publicado: (2018)

Virus Infections Play Crucial Roles in the Pathogenesis of Sjögren’s Syndrome
por: Otsuka, Kunihiro, et al.
Publicado: (2022)

Formation of Autoimmune Lesions Is Independent of Antibiotic Treatment in NOD Mice
por: Sato, Mami, et al.
Publicado: (2021)

Unique Phenotypes and Functions of Follicular Helper T Cells and Regulatory T Cells in Sjögren’s Syndrome
por: Saito, Masako, et al.
Publicado: (2018)

Long-term polarization of alveolar macrophages to a profibrotic phenotype after inhalation exposure to multi-wall carbon nanotubes
por: Otsuka, Kunihiro, et al.
Publicado: (2018)

Pathological Analysis of Ocular Lesions in a Murine Model of Sjögren’s Syndrome
por: Ushio, Aya, et al.
Publicado: (2017)

The Non-Canonical Role of Aurora-A in DNA Replication
por: Tsunematsu, Takaaki, et al.
Publicado: (2015)

Cancer cell‐derived novel periostin isoform promotes invasion in head and neck squamous cell carcinoma
por: Wenhua, Shao, et al.
Publicado: (2023)

Molecular Mechanisms of Nickel Allergy
por: Saito, Masako, et al.
Publicado: (2016)

Expression of the retinoblastoma protein RbAp48 in exocrine glands leads to Sjögren's syndrome–like autoimmune exocrinopathy
por: Ishimaru, Naozumi, et al.
Publicado: (2008)

Preventive effects of mouthguard use while sleeping on recurrent aphthous stomatitis: Preliminary interventional study
por: Tada, Hidesuke, et al.
Publicado: (2017)

Chemokines Up-Regulated in Epithelial Cells Control Senescence-Associated T Cell Accumulation in Salivary Glands of Aged and Sjögren’s Syndrome Model Mice
por: Kurosawa, Mie, et al.
Publicado: (2021)

APC/C(Cdh1) is required for the termination of chromosomal passenger complex activity upon mitotic exit
por: Tsunematsu, Takaaki, et al.
Publicado: (2020)

Anti-Inflammatory Effects of Rebamipide Eyedrop Administration on Ocular Lesions in a Murine Model of Primary Sjögren's Syndrome
por: Arakaki, Rieko, et al.
Publicado: (2014)

Cathepsin L Inhibition Prevents Murine Autoimmune Diabetes via Suppression of CD8(+) T Cell Activity
por: Yamada, Akiko, et al.
Publicado: (2010)

Dual Role of Fas/FasL-Mediated Signal in Peripheral Immune Tolerance
por: Yamada, Akiko, et al.
Publicado: (2017)

Aurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis
por: Tsunematsu, Takaaki, et al.
Publicado: (2013)

Invasion-Related Factors as Potential Diagnostic and Therapeutic Targets in Oral Squamous Cell Carcinoma—A Review
por: Siriwardena, Samadarani B. S. M., et al.
Publicado: (2018)

Potential Role of Free Fatty Acids in the Pathogenesis of Periodontitis and Primary Sjögren’s Syndrome
por: Shikama, Yosuke, et al.
Publicado: (2017)

In Situ Patrolling of Regulatory T Cells Is Essential for Protecting Autoimmune Exocrinopathy
por: Ishimaru, Naozumi, et al.
Publicado: (2010)

Oral environment and cancer
por: Kudo, Yasusei, et al.
Publicado: (2016)

A Novel DC Therapy with Manipulation of MKK6 Gene on Nickel Allergy in Mice
por: Watanabe, Megumi, et al.
Publicado: (2011)

Protective effects of resveratrol against 5-fluorouracil-induced oxidative stress and inflammatory responses in human keratinocytes
por: Chen, Shu, et al.
Publicado: (2021)

Stratifying primary Sjögren’s syndrome: killers in the balance?
por: Bowman, Simon J., et al.
Publicado: (2015)

Fas-Independent T-Cell Apoptosis by Dendritic Cells Controls Autoimmune Arthritis in MRL/lpr Mice
por: Izawa, Takashi, et al.
Publicado: (2012)

Coordination of WNT signaling and ciliogenesis during odontogenesis by piezo type mechanosensitive ion channel component 1
por: Miyazaki, Aya, et al.
Publicado: (2019)

The microRNA-15a-PAI-2 axis in cholangiocarcinoma-associated fibroblasts promotes migration of cancer cells
por: Utaijaratrasmi, Penkhae, et al.
Publicado: (2018)

Regulation of sepsis-induced IFNγ upon natural killer cell or natural killer T cell depletion in vivo
por: Christaki, E, et al.
Publicado: (2012)

PARP6 acts as a tumor suppressor via downregulating Survivin expression in colorectal cancer
por: Qi, Guangying, et al.
Publicado: (2016)

Disturbance of cytokine networks in Sjögren's syndrome
por: Youinou, Pierre, et al.
Publicado: (2011)

The thymoproteasome hardwires the TCR repertoire of CD8(+) T cells in the cortex independent of negative selection
por: Ohigashi, Izumi, et al.
Publicado: (2021)

Smell and Taste Function and Their Disturbances in Sjögren’s Syndrome
por: Błochowiak, Katarzyna
Publicado: (2022)

Periostin Directly and Indirectly Promotes Tumor Lymphangiogenesis of Head and Neck Cancer
por: Kudo, Yasusei, et al.
Publicado: (2012)

Matrix Metalloproteinases: The Gene Expression Signatures of Head and Neck Cancer Progression
por: Iizuka, Shinji, et al.
Publicado: (2014)

Injuries in Collegiate Track and Field Jumping: A 2-Year Prospective Surveillance Study
por: Enoki, Shota, et al.
Publicado: (2021)

Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells
por: Höfle, Johannes, et al.
Publicado: (2022)

The immunohistochemical detection of peroxiredoxin 1 and 2 in canine spontaneous vascular endothelial tumors
por: OTSUKA, Narumi, et al.
Publicado: (2022)

The PP2A inhibitor SET regulates natural killer cell IFN-γ production
por: Trotta, Rossana, et al.
Publicado: (2007)

Natural Killer Cells in Afferent Lymph Express an Activated Phenotype and Readily Produce IFN-γ
por: Lund, Hege, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_s64cckm095gf85fht3e4bkg7lk