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Sunitinib induced hepatotoxicity in L02 cells via ROS-MAPKs signaling pathway
Sunitinib is a multi-targeted tyrosine kinase inhibitor with remarkable anticancer activity, while hepatotoxicity is a potentially fatal adverse effect of its administration. The aim of this study was to elucidate the mechanism of hepatotoxicity induced by Sunitinib and the protective effect of glyc...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643779/ https://www.ncbi.nlm.nih.gov/pubmed/36386201 http://dx.doi.org/10.3389/fphar.2022.1002142 |