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Sunitinib induced hepatotoxicity in L02 cells via ROS-MAPKs signaling pathway

Sunitinib is a multi-targeted tyrosine kinase inhibitor with remarkable anticancer activity, while hepatotoxicity is a potentially fatal adverse effect of its administration. The aim of this study was to elucidate the mechanism of hepatotoxicity induced by Sunitinib and the protective effect of glyc...

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Detalles Bibliográficos
Autores principales:	Tang, Ting-Li, Yang, Yan, Guo, Lin, Xia, Shuang, Zhang, Bikui, Yan, Miao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643779/ https://www.ncbi.nlm.nih.gov/pubmed/36386201 http://dx.doi.org/10.3389/fphar.2022.1002142

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