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Peptide nanotube loaded with a STING agonist, c-di-GMP, enhance cancer immunotherapy against melanoma
The activation of the stimulating factor of the interferon gene (STING) pathway can enhance the immune response within the tumor. Cyclic diguanylate monophosphate (c-di-GMP) is a negatively charged, hydrophilic STING agonist, however, its effectiveness is limited due to the poor membrane permeabilit...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tsinghua University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643898/ https://www.ncbi.nlm.nih.gov/pubmed/36405984 http://dx.doi.org/10.1007/s12274-022-5102-z |