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Peptide nanotube loaded with a STING agonist, c-di-GMP, enhance cancer immunotherapy against melanoma

The activation of the stimulating factor of the interferon gene (STING) pathway can enhance the immune response within the tumor. Cyclic diguanylate monophosphate (c-di-GMP) is a negatively charged, hydrophilic STING agonist, however, its effectiveness is limited due to the poor membrane permeabilit...

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Detalles Bibliográficos
Autores principales: Zhang, Ziyuan, Liu, Juan, Xiao, Min, Zhang, Quanfeng, Liu, Zhonghua, Liu, Meiyan, Zhang, Peng, Zeng, Youlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tsinghua University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643898/
https://www.ncbi.nlm.nih.gov/pubmed/36405984
http://dx.doi.org/10.1007/s12274-022-5102-z