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Elongator promotes neuritogenesis via regulation of tau stability through acly activity
The six subunits (Elp1 to Elp6) Elongator complex promotes specific uridine modifications in tRNA’s wobble site. Moreover, this complex has been indirectly involved in the regulation of α-tubulin acetylation in microtubules (MTs) via the stabilization of ATP-Citrate Lyase (Acly), the main cytosolic...
Autores principales: | Shilian, Michal, Even, Aviel, Gast, Hila, Nguyen, Laurent, Weil, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644021/ https://www.ncbi.nlm.nih.gov/pubmed/36393857 http://dx.doi.org/10.3389/fcell.2022.1015125 |
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