Translation suppression underlies the restrained COVID-19 mRNA vaccine response in the high-risk immunocompromised group

BACKGROUND: Immunocompromised (IC) patients show diminished immune response to COVID-19 mRNA vaccines (Co-mV). To date, there is no ‘empirical’ evidence to link the perturbation of translation, a rate-limiting step for mRNA vaccine efficiency (VE), to the dampened response of Co-mV. MATERIALS AND ME...

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Detalles Bibliográficos
Autores principales: Kim, Kangsan, Narasimhan, Madhusudhanan, Mahimainathan, Lenin, Zhang, Ray, Araj, Ellen, Kim, Elizabeth, Tharpe, William, Greenberg, Benjamin M., Greenberg, David E., Li, Quan-Zhen, Cheng, Chi-An, Sarode, Ravi, Malladi, Srinivas, Muthukumar, Alagarraju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644109/
https://www.ncbi.nlm.nih.gov/pubmed/36389788
http://dx.doi.org/10.3389/fimmu.2022.1020165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644109/
https://www.ncbi.nlm.nih.gov/pubmed/36389788
http://dx.doi.org/10.3389/fimmu.2022.1020165

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