Cargando…

Differential H3K9me2 heterochromatin levels and concordant mRNA expression in postmortem brain tissue of individuals with schizophrenia, bipolar, and controls

The existence of repressive and durable chromatin assemblies along gene promoters or networks, especially in the brain, is of theoretical and therapeutic relevance in a subset of individuals diagnosed with schizophrenia who experience a chronic, persistent, and treatment-resistant trajectory. We use...

Descripción completa

Detalles Bibliográficos
Autores principales: Rizavi, Hooriyah S., Chase, Kayla A., Liu, Chunyu, Gavin, Hannah, Rosen, Cherise, Xia, Cuihua, Guidotti, Alessandro, Sharma, Rajiv P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644155/
https://www.ncbi.nlm.nih.gov/pubmed/36386965
http://dx.doi.org/10.3389/fpsyt.2022.1006109