A transcriptional program associated with cell cycle regulation predominates in the anti-inflammatory effects of CX-5461 in macrophage

CX-5461, a novel selective RNA polymerase I inhibitor, shows potential anti-inflammatory and immunosuppressive activities. However, the molecular mechanisms underlying the inhibitory effects of CX-5461 on macrophage-mediated inflammation remain to be clarified. In the present study, we attempted to...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Zheng, Zhijian, Cui, Xiaopei, Dai, Chaochao, Li, Jiaxin, Zhang, Qunye, Cheng, Mei, Jiang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644203/
https://www.ncbi.nlm.nih.gov/pubmed/36386132
http://dx.doi.org/10.3389/fphar.2022.926317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644203/
https://www.ncbi.nlm.nih.gov/pubmed/36386132
http://dx.doi.org/10.3389/fphar.2022.926317

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