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Endostatin induces normalization of blood vessels in colorectal cancer and promotes infiltration of CD8+ T cells to improve anti-PD-L1 immunotherapy

INTRODUCTION: The purpose of this study was to evaluate recombinant human endostatin (rHE)-induced normalization of the tumor vasculature in colorectal cancer (CRC) and to evaluate the therapeutic effects of combined treatment with rHE and a programmed death ligand-1 (PD-L1) inhibitor. METHODS: A mo...

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Detalles Bibliográficos
Autores principales: Chu, Xiao-Dong, Bao, Hui, Lin, Yu-Jian, Chen, Ruo-Xi, Zhang, Yi-Ran, Huang, Ting, He, Jia-Shuai, Huangfu, Shu-Chen, Pan, Yun-Long, Ding, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644205/
https://www.ncbi.nlm.nih.gov/pubmed/36389685
http://dx.doi.org/10.3389/fimmu.2022.965492