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Myokines derived from contracting skeletal muscle suppress anabolism in MCF7 breast cancer cells by inhibiting mTOR

Summary: There is strong evidence that physical activity has a profound protective effect against multiple types of cancer. Here, we show that this effect may be mediated by factors released from skeletal muscle during simulated exercise, in situ, which suppress canonical anabolic signaling in breas...

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Detalles Bibliográficos
Autores principales: Davis, Amanda R., Goodenough, Chelsea G., Westerlind, Kim C., Strange, Robert, Deaver, John W., Ryan, Patrick J., Riechman, Steven E., Fluckey, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644210/
https://www.ncbi.nlm.nih.gov/pubmed/36388131
http://dx.doi.org/10.3389/fphys.2022.1033585