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Myokines derived from contracting skeletal muscle suppress anabolism in MCF7 breast cancer cells by inhibiting mTOR
Summary: There is strong evidence that physical activity has a profound protective effect against multiple types of cancer. Here, we show that this effect may be mediated by factors released from skeletal muscle during simulated exercise, in situ, which suppress canonical anabolic signaling in breas...
Autores principales: | Davis, Amanda R., Goodenough, Chelsea G., Westerlind, Kim C., Strange, Robert, Deaver, John W., Ryan, Patrick J., Riechman, Steven E., Fluckey, James D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644210/ https://www.ncbi.nlm.nih.gov/pubmed/36388131 http://dx.doi.org/10.3389/fphys.2022.1033585 |
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