Cargando…

Transdermal Delivery of Succinate Accelerates Energy Dissipation of Brown Adipocytes to Reduce Remote Fat Accumulation

[Image: see text] Weight loss by increasing energy consumption of thermogenic adipocytes to overcome obesity remains a challenge. Herein, we established a transdermal device that was based on the local and temporarily controlled delivery of succinate (SC), a tricarboxylic acid cycle metabolic interm...

Descripción completa

Detalles Bibliográficos
Autores principales: Liao, Fang-Hsuean, Yao, Chun-Nien, Chen, Shu-Ping, Wu, Te-Haw, Lin, Shu-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644396/
https://www.ncbi.nlm.nih.gov/pubmed/36281715
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00628