Cargando…
Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing
Multiple myeloma is a plasma cell neoplasm characterized by clonal immunoglobulin V(D)J signatures and oncogenic immunoglobulin gene translocations. Additional subclonal genomic changes are acquired with myeloma progression and therapeutic selection. PCR-based methods to detect V(D)J rearrangements...
Autores principales: | Chow, Signy, Kis, Olena, Mulder, David T, Danesh, Arnavaz, Bruce, Jeff, Wang, Ting Ting, Reece, Donna, Bhalis, Nizar, Neri, Paola, Sabatini, Peter JB, Keats, Jonathan, Trudel, Suzanne, Pugh, Trevor J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644417/ https://www.ncbi.nlm.nih.gov/pubmed/36328595 http://dx.doi.org/10.26508/lsa.202201543 |
Ejemplares similares
-
Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates
por: Kis, Olena, et al.
Publicado: (2017) -
Multiple myeloma immunoglobulin lambda translocations portend poor prognosis
por: Barwick, Benjamin G., et al.
Publicado: (2019) -
A comprehensive molecular cytogenetic analysis of chromosome rearrangements in gibbons
por: Capozzi, Oronzo, et al.
Publicado: (2012) -
Genome sequencing of C. elegans balancer strains reveals previously unappreciated complex genomic rearrangements
por: Maroilley, Tatiana, et al.
Publicado: (2023) -
Global mitochondrial protein import proteomics reveal distinct regulation by translation and translocation machinery
por: Schäfer, Jasmin Adriana, et al.
Publicado: (2022)