C-to-U RNA deamination is the driving force accelerating SARS-CoV-2 evolution

Understanding the molecular mechanism underlying the rampant mutation of SARS-CoV-2 would help us control the COVID-19 pandemic. The APOBEC-mediated C-to-U deamination is a major mutation type in the SARS-CoV-2 genome. However, it is unclear whether the novel mutation rate u is higher for C-to-U tha...

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Detalles Bibliográficos
Autores principales: Li, Yan, Hou, Fanghua, Zhou, Meili, Yang, Xiaoping, Yin, Bin, Jiang, Wenqing, Xu, Huiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644418/
https://www.ncbi.nlm.nih.gov/pubmed/36347544
http://dx.doi.org/10.26508/lsa.202201688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644418/
https://www.ncbi.nlm.nih.gov/pubmed/36347544
http://dx.doi.org/10.26508/lsa.202201688

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