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C-to-U RNA deamination is the driving force accelerating SARS-CoV-2 evolution
Understanding the molecular mechanism underlying the rampant mutation of SARS-CoV-2 would help us control the COVID-19 pandemic. The APOBEC-mediated C-to-U deamination is a major mutation type in the SARS-CoV-2 genome. However, it is unclear whether the novel mutation rate u is higher for C-to-U tha...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Life Science Alliance LLC
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644418/ https://www.ncbi.nlm.nih.gov/pubmed/36347544 http://dx.doi.org/10.26508/lsa.202201688 |