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Elevation of spermine remodels immunosuppressive microenvironment through driving the modification of PD-L1 in hepatocellular carcinoma

BACKGROUND: Spermine is frequently elevated in tumor tissues and body fluids of cancer patients and is critical for cancer cell proliferation, migration and invasion. However, the immune functions of spermine in hepatocellular carcinoma progression remains unknown. In the present study, we aimed to...

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Detalles Bibliográficos
Autores principales: Shi, Hong-Xiang, Liang, Chao, Yao, Chao-Yan, Gao, Zi-Xuan, Qin, Jia, Cao, Jin-Lan, Zhang, Ming-Zhu, Li, Ying-Ying, Wang, Meng-Qing, Sun, Hua, Xie, Song-Qiang, Fang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644467/
https://www.ncbi.nlm.nih.gov/pubmed/36348350
http://dx.doi.org/10.1186/s12964-022-00981-6