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Inhibition of AEBP1 predisposes cisplatin-resistant oral cancer cells to ferroptosis

BACKGROUND: Studies have shown that excessive iron can lead to an increased incidence of cancer. The role of adipocyte enhancer-binding protein 1 (AEBP1) on ferroptosis is unknown. Thus, we explored the effect of AEBP1 silencing in regulation of ferroptosis in cisplatin-resistant oral cancer cells....

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Detalles Bibliográficos
Autores principales: Zhou, Qianwen, Wang, Xiaoqi, Zhang, Yingxue, Wang, Lie, Chen, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644533/
https://www.ncbi.nlm.nih.gov/pubmed/36352396
http://dx.doi.org/10.1186/s12903-022-02503-9