CAFs-derived SCUBE1 promotes malignancy and stemness through the Shh/Gli1 pathway in hepatocellular carcinoma

BACKGROUND: The tumour microenvironment and cirrhotic liver are excellent sources of cancer-associated fibroblasts (CAFs), which participate in carcinogenesis. Thus, it is important to clarify the crosstalk between CAFs and HCC cells and the related mechanism in regulating carcinogenesis. METHODS: H...

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Detalles Bibliográficos
Autores principales: Zhao, Jungang, Li, Rizhao, Li, Jiacheng, Chen, Ziyan, Lin, Zixia, Zhang, Baofu, Deng, Liming, Chen, Gang, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644546/
https://www.ncbi.nlm.nih.gov/pubmed/36348351
http://dx.doi.org/10.1186/s12967-022-03689-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644546/
https://www.ncbi.nlm.nih.gov/pubmed/36348351
http://dx.doi.org/10.1186/s12967-022-03689-w

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