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CAFs-derived SCUBE1 promotes malignancy and stemness through the Shh/Gli1 pathway in hepatocellular carcinoma

BACKGROUND: The tumour microenvironment and cirrhotic liver are excellent sources of cancer-associated fibroblasts (CAFs), which participate in carcinogenesis. Thus, it is important to clarify the crosstalk between CAFs and HCC cells and the related mechanism in regulating carcinogenesis. METHODS: H...

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Detalles Bibliográficos
Autores principales:	Zhao, Jungang, Li, Rizhao, Li, Jiacheng, Chen, Ziyan, Lin, Zixia, Zhang, Baofu, Deng, Liming, Chen, Gang, Wang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644546/ https://www.ncbi.nlm.nih.gov/pubmed/36348351 http://dx.doi.org/10.1186/s12967-022-03689-w

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