Bone marrow mesenchymal stem cell-derived exosomes shuttling miR-150-5p alleviates mechanical allodynia in rats by targeting NOTCH2 in microglia

BACKGROUND: This study probes into the function and mechanism of bone marrow mesenchymal stem cell (BMSC)-derived exosomes loaded with miR-150-5p in mechanical allodynia. METHODS: BMSCs were infected with miR-150-5p inhibition lentiviruses to obtain exosomes with low miR-150-5p expression. A L5 spin...

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Detalles Bibliográficos
Autores principales: Li, Shuangqing, Huang, Ciying, Tu, Chao, Chen, Ruiqi, Ren, Xiaolei, Qi, Lin, Li, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644547/
https://www.ncbi.nlm.nih.gov/pubmed/36348269
http://dx.doi.org/10.1186/s10020-022-00561-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644547/
https://www.ncbi.nlm.nih.gov/pubmed/36348269
http://dx.doi.org/10.1186/s10020-022-00561-x

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