Cargando…
Bone marrow mesenchymal stem cell-derived exosomes shuttling miR-150-5p alleviates mechanical allodynia in rats by targeting NOTCH2 in microglia
BACKGROUND: This study probes into the function and mechanism of bone marrow mesenchymal stem cell (BMSC)-derived exosomes loaded with miR-150-5p in mechanical allodynia. METHODS: BMSCs were infected with miR-150-5p inhibition lentiviruses to obtain exosomes with low miR-150-5p expression. A L5 spin...
Autores principales: | Li, Shuangqing, Huang, Ciying, Tu, Chao, Chen, Ruiqi, Ren, Xiaolei, Qi, Lin, Li, Zhihong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644547/ https://www.ncbi.nlm.nih.gov/pubmed/36348269 http://dx.doi.org/10.1186/s10020-022-00561-x |
Ejemplares similares
-
Notch1 Signaling Contributes to Mechanical Allodynia Associated with Cyclophosphamide-Induced Cystitis by Promoting Microglia Activation and Neuroinflammation
por: Chen, Jialiang, et al.
Publicado: (2021) -
LncRNA MALAT1 shuttled by bone marrow-derived mesenchymal stem cells-secreted exosomes alleviates osteoporosis through mediating microRNA-34c/SATB2 axis
por: Yang, Xucheng, et al.
Publicado: (2019) -
Activation of Notch1 signaling alleviates dysfunction of bone marrow-derived mesenchymal stem cells induced by cigarette smoke extract
por: Cheng, Yi, et al.
Publicado: (2017) -
BDNF promotes activation of astrocytes and microglia contributing to neuroinflammation and mechanical allodynia in cyclophosphamide-induced cystitis
por: Ding, Honglu, et al.
Publicado: (2020) -
Exosomes derived from heat shock preconditioned bone marrow mesenchymal stem cells alleviate cisplatin-induced ototoxicity in mice
por: Yang, Tao, et al.
Publicado: (2022)