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Ligand-gated ion channel P2X7 regulates hypoxia-induced factor-1α mediated pain induced by dental pulpitis in the medullary dorsal horn

Dental pulpitis often induces severe pain, and the molecular immune response is remarkable in both peripheral and central nervous system. Accumulating evidence indicates that activated microglia in the medullary dorsal horn (MDH) contribute to dental pulpitis induced pain. The P2X7 receptor plays an...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Si, Jialin, Liang, Rongrong, Lu, Yuxin, Shang, Hongwei, Li, Xinwei, Sun, Shukai, Wu, Li-an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644926/
https://www.ncbi.nlm.nih.gov/pubmed/36385758
http://dx.doi.org/10.3389/fnmol.2022.1015751