Engineering a pure and stable heterodimeric IgA for the development of multispecific therapeutics

Immunoglobulin G (IgG) has served as a traditional framework for antibody-based biology, and engineering approaches for creating multispecific therapeutics have greatly expanded its applicability. Despite these developments, there are limits to the functionality of IgG with respect to effector cells...

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Detalles Bibliográficos
Autores principales: Heinkel, Florian, Verstraete, Meghan M., Cao, Siran, Li, Janessa, Farber, Patrick, Stangle, Elizabeth, Silva-Moreno, Begonia, Peng, Fangni, Dixit, Surjit, Boulanger, Martin J., Spreter Von Kreudenstein, Thomas, Escobar-Cabrera, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645255/
https://www.ncbi.nlm.nih.gov/pubmed/36343329
http://dx.doi.org/10.1080/19420862.2022.2141637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645255/
https://www.ncbi.nlm.nih.gov/pubmed/36343329
http://dx.doi.org/10.1080/19420862.2022.2141637

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