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Engineering a pure and stable heterodimeric IgA for the development of multispecific therapeutics
Immunoglobulin G (IgG) has served as a traditional framework for antibody-based biology, and engineering approaches for creating multispecific therapeutics have greatly expanded its applicability. Despite these developments, there are limits to the functionality of IgG with respect to effector cells...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645255/ https://www.ncbi.nlm.nih.gov/pubmed/36343329 http://dx.doi.org/10.1080/19420862.2022.2141637 |