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Model-informed precision dosing of beta-lactam antibiotics and ciprofloxacin in critically ill patients: a multicentre randomised clinical trial

PURPOSE: Individualising drug dosing using model-informed precision dosing (MIPD) of beta-lactam antibiotics and ciprofloxacin has been proposed as an alternative to standard dosing to optimise antibiotic efficacy in critically ill patients. However, randomised clinical trials (RCT) on clinical outc...

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Detalles Bibliográficos
Autores principales: Ewoldt, Tim M. J., Abdulla, Alan, Rietdijk, Wim J. R., Muller, Anouk E., de Winter, Brenda C. M., Hunfeld, Nicole G. M., Purmer, Ilse M., van Vliet, Peter, Wils, Evert-Jan, Haringman, Jasper, Draisma, Annelies, Rijpstra, Tom A., Karakus, Attila, Gommers, Diederik, Endeman, Henrik, Koch, Birgit C. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645317/
https://www.ncbi.nlm.nih.gov/pubmed/36350354
http://dx.doi.org/10.1007/s00134-022-06921-9