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The Potential Protective Role of GS-441524, a Metabolite of the Prodrug Remdesivir, in Vaccine Breakthrough SARS-CoV-2 Infections

Cases of vaccine breakthrough, especially in variants of concern (VOCs) infections, are emerging in coronavirus disease (COVID-19). Due to mutations of structural proteins (SPs) (e.g., Spike proteins), increased transmissibility and risk of escaping from vaccine-induced immunity have been reported a...

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Detalles Bibliográficos
Autores principales: Zhu, JiaYi, Li, Yuchong, Liang, Jady, Mubareka, Samira, Slutsky, Arthur S., Zhang, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645326/
https://www.ncbi.nlm.nih.gov/pubmed/36407474
http://dx.doi.org/10.1007/s44231-022-00021-4