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Pattern enrichment analysis for phage selection of stapled peptide ligands

Phage display is the most widely used technique to discover de novo peptides that bind to target proteins. However, it is associated with some challenges such as compositional bias. In this study, to overcome these difficulties, we devised a ‘pattern enrichment analysis.’ In this method, two samples...

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Detalles Bibliográficos
Autores principales: Miki, Takayuki, Namii, Keigo, Seko, Kenta, Kakehi, Shota, Moro, Goshi, Mihara, Hisakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645375/
https://www.ncbi.nlm.nih.gov/pubmed/36519040
http://dx.doi.org/10.1039/d2sc04058a