Design, molecular docking, drug-likeness, and molecular dynamics studies of 1,2,4-trioxane derivatives as novel Plasmodium falciparum falcipain-2 (FP-2) inhibitors

Despite significant progress made in drug discovery and development over the past few decades, malaria remains a life-threatening infectious disease across the globe. Because of the widespread emergence of drug-resistant strains of Plasmodium falciparum, the clinical utility of existing drug therapi...

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Detalles Bibliográficos
Autores principales: Ghosh, Subham, Chetia, Dipak, Gogoi, Neelutpal, Rudrapal, Mithun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645569/
https://www.ncbi.nlm.nih.gov/pubmed/36606151
http://dx.doi.org/10.5114/bta.2021.108722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645569/
https://www.ncbi.nlm.nih.gov/pubmed/36606151
http://dx.doi.org/10.5114/bta.2021.108722

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