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TGFβ: Signaling Blockade for Cancer Immunotherapy
Discovered over four decades ago, transforming growth factor β (TGFβ) is a potent pleiotropic cytokine that has context-dependent effects on most cell types. It acts as a tumor suppressor in some cancers and/or supports tumor progression and metastasis through its effects on the tumor stroma and imm...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645596/ https://www.ncbi.nlm.nih.gov/pubmed/36382146 http://dx.doi.org/10.1146/annurev-cancerbio-070620-103554 |