The in silico and in vitro analysis of donepezil derivatives for Anopheles acetylcholinesterase inhibition

Current studies on Anopheles anticholinesterase insecticides are focusing on identifying agents with high selectivity towards Anopheles over mammalian targets. Acetylcholinesterase (AChE) from electric eel is often used as the bioequivalent enzyme to study ligands designed for activity and inhibitio...

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Detalles Bibliográficos
Autores principales: Rants’o, Thankhoe A., van Greunen, Divan G., van der Westhuizen, C. Johan, Riley, Darren L., Panayides, Jenny-Lee, Koekemoer, Lizette L., van Zyl, Robyn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645637/
https://www.ncbi.nlm.nih.gov/pubmed/36350894
http://dx.doi.org/10.1371/journal.pone.0277363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645637/
https://www.ncbi.nlm.nih.gov/pubmed/36350894
http://dx.doi.org/10.1371/journal.pone.0277363

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