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The in silico and in vitro analysis of donepezil derivatives for Anopheles acetylcholinesterase inhibition
Current studies on Anopheles anticholinesterase insecticides are focusing on identifying agents with high selectivity towards Anopheles over mammalian targets. Acetylcholinesterase (AChE) from electric eel is often used as the bioequivalent enzyme to study ligands designed for activity and inhibitio...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645637/ https://www.ncbi.nlm.nih.gov/pubmed/36350894 http://dx.doi.org/10.1371/journal.pone.0277363 |