Structure-based virtual screening and molecular dynamics of potential inhibitors targeting sodium-bile acid co-transporter of carcinogenic liver fluke Clonorchis sinensis

BACKGROUND: Clonorchis sinensis requires bile acid transporters as this fluke inhabits bile juice-filled biliary ducts, which provide an extreme environment. Clonorchis sinensis sodium-bile acid co-transporter (CsSBAT) is indispensable for the fluke’s survival in the final host, as it circulates tau...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoo, Won Gi, Dai, Fuhong, Pak, Jhang Ho, Hong, Sung-Jong, Song, Jin-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645658/
https://www.ncbi.nlm.nih.gov/pubmed/36350897
http://dx.doi.org/10.1371/journal.pntd.0010909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645658/
https://www.ncbi.nlm.nih.gov/pubmed/36350897
http://dx.doi.org/10.1371/journal.pntd.0010909

Ejemplares similares