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Dual role of an essential HtrA2/Omi protease in the human malaria parasite: Maintenance of mitochondrial homeostasis and induction of apoptosis-like cell death under cellular stress

Members of the HtrA family of serine proteases are known to play roles in mitochondrial homeostasis as well as in programmed cell death. Mitochondrial homeostasis and metabolism are crucial for the survival and propagation of the malaria parasite within the host. Here we have functionally characteri...

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Detalles Bibliográficos
Autores principales: Singh, Shweta, Datta, Gaurav, Jain, Shaifali, Thakur, Vandana, Arora, Priya, Muneer, Azhar, Asad, Mohd, Ali, Shakir, Mohmmed, Asif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645662/
https://www.ncbi.nlm.nih.gov/pubmed/36306288
http://dx.doi.org/10.1371/journal.ppat.1010932